Ozonated glycerin is glycerin that has been infused with ozone (O₃). It’s used topically in some alternative and integrative skin-care settings because it combines glycerin’s moisturizing properties with ozone’s antimicrobial and oxidative activity. Below is a condition-by-condition overview, with benefits, proposed mechanisms, and important cautions.

How ozonated glycerin works (in simple terms)

• Antimicrobial action: Ozone can inactivate bacteria, fungi, viruses, and some parasites by oxidizing their cell membranes.

• Anti-inflammatory signaling (indirect): Low, controlled oxidative stress may modulate inflammatory pathways.

• Improved skin barrier: Glycerin is a humectant, helping the skin retain moisture and supporting healing.

• Enhanced oxygen metabolism (theoretical): Ozone may improve local tissue oxygen utilization, which can support wound repair.

  
  

Reported benefits by condition

1. Skin conditions & minor wounds

• Helps cleanse and protect compromised skin

• May reduce microbial load without antibiotics

• Glycerin reduces dryness and cracking

Use case: minor cuts, abrasions, irritated skin (not deep wounds)

2. Burns (minor to moderate, non-critical)

• Antimicrobial protection against infection

• May support faster epithelial healing

• Keeps burned skin hydrated, reducing cracking

Important:

• Do not use on severe, deep, or extensive burns without medical supervision.

  
  

3. Allergic dermatitis

• May reduce itching and redness

• Helps calm skin by lowering secondary bacterial involvement

• Moisturization improves barrier recovery

4. Eczema

• Can reduce itching and dryness

• Antimicrobial effect may help when eczema is complicated by bacterial overgrowth

• Glycerin supports barrier repair

Caution:

• Some people with eczema are sensitive to oxidative products—patch test first.

5. Psoriasis

• May help with:

  • Scaling

  • Secondary infections

  • Local inflammation

• Glycerin softens plaques, improving comfort

6. Shingles (Herpes zoster – external use only)

• Ozone’s antiviral properties may:

  • Reduce viral load on the skin

  • Lower risk of secondary infection

• Can soothe lesions and dryness

Important:

• This is supportive care only, not a replacement for antiviral medications (e.g., acyclovir).

7. Snake bites

• Not a primary treatment

• Potential topical benefits:

  • Reduce microbial contamination at the bite site

• Does NOT neutralize venom

🚨 Snake bites are medical emergencies — ozonated glycerin should only be considered after emergency treatment and only for superficial skin care.

8. Insect bites

• Reduces:

  • Itching

  • Redness

  • Risk of infection from scratching

• Antimicrobial + soothing effects work well here

9. Poison oak & poison ivy

• Calm inflammation and itching

• Help prevent secondary infection

• Glycerin supports healing of weepy or cracked skin

Tip:

• Wash exposed skin first to remove urushiol oil before applying anything.

Added component: DMSO (Dimethyl Sulfoxide)

DMSO is a highly penetrative solvent derived from lignin (wood pulp) that is sometimes used topically in integrative and veterinary settings. When included in a formulation like ozonated glycerin, it can significantly influence absorption and activity at the skin level.

How DMSO works (in simple terms)

• Powerful penetration enhancer:DMSO can carry small molecules through the skin barrier and into deeper tissues.

• Anti-inflammatory effects:It may reduce pain, swelling, and inflammatory signaling at the application site.

• Free-radical scavenging:DMSO can neutralize certain reactive oxygen species, potentially balancing oxidative stress when used appropriately.

• Analgesic (pain-reducing) properties:Often reported to reduce localized pain and discomfort.

Benefits of adding DMSO to ozonated glycerin

1. Enhanced delivery of ozone-derived compounds

• May allow ozone byproducts (ozonides, peroxides) to penetrate more deeply into tissue

• Could improve effectiveness for stubborn or chronic skin issues

2. Improved results for inflammatory skin conditions

May support relief in conditions involving:

• Eczema-related inflammation

• Psoriasis discomfort

• Allergic or irritant dermatitis

• Painful insect bites or stings

3. Pain and discomfort reduction

• May help reduce:

  • Burning

  • Itching

  • Tenderness

  • Localized pain from minor injuries or skin irritation

4. Support for slow-healing or compromised skin

• Enhanced penetration + glycerin hydration may support:

  • Minor wounds

  • Cracked or thickened skin

  • Areas with poor circulation (non-critical)

Safety notes & cautions

• Topical use only (unless directed by a trained professional)

• Patch test before widespread application

• Avoid eyes, mucous membranes, and deep open wounds

• Over-oxidation or frequent use may cause irritation in sensitive skin

• Not a substitute for medical care in serious conditions